Less writing overhead.
More breakthrough science.
River is the AI workspace for scientists, PhDs, and PIs. Connect your papers, lab notes, and data — then let AI help you write grants, draft manuscripts, synthesize literature, and document protocols, so you can spend your time actually doing research.
DocsSpecific Aims — NIH R01 Application
Despite advances in targeted therapy, acquired resistance to EGFR inhibitors remains the primary driver of treatment failure in non-small cell lung cancer (NSCLC), affecting ~70% of patients within 18 months of initial response.
Aim 1
Characterize the transcriptomic landscape of resistant NSCLC tumors using single-cell RNA sequencing across a cohort of 120 patients with acquired osimertinib resistance.
Aim 2
Identify novel combination strategies by integrating multi-omics data with a high-throughput drug screening platform targeting the top resistance mechanisms identified in Aim 1.
Aim 3
Validate lead combinations in patient-derived organoid models and assess pharmacokinetics in preclinical in vivo studies to establish proof-of-concept for IND-enabling studies.
The status quo
What slows researchers down today
- Writing takes 40% of your research timeStudies show academic researchers spend nearly half their working hours on grants, reports, manuscript revisions, reviewer responses, and documentation — not actual science.
- Staring at a blank page two weeks before the NIH deadlineEvery grant cycle ends the same way: the Specific Aims get written in a panic, the Significance section is vague, and the Innovation section barely exists.
- Your AI tool doesn't know your researchChatGPT gives you generic boilerplate with your name pasted in. It hasn't read your publications, doesn't know your preliminary data, and has never seen your prior grants.
- Literature review takes days of re-reading the same abstractsSynthesizing 200 papers requires keeping track of contradictions, gaps, and consensus across a field — impossible to hold in your head and tedious to do manually.
- New lab members get up to speed slowlyYour bench protocols are in someone's notebook. Your SOPs are in a Word document from 2019. New grad students spend months re-discovering things your lab already knows.
- Administrative writing never advances your scienceIRB applications, annual progress reports, data management plans — the paperwork has to get done, but every hour spent on it is an hour away from the bench.
The work, organized
What researchers use River for
Start here
Research Lab Space
A ready-to-use Space built for the full research lifecycle — from grant application through publication, with your reference library and lab documentation in context.
Included
- NIH R01 grant application template
- Manuscript drafting workspace
- Literature review synthesis doc
- Lab SOP and protocol templates
- Zotero + Google Drive integration
- PI review and co-author sharing
How River works
Everything lives inside a Space
A River Space holds your reference library, manuscripts, data, notes, and protocols in one place. When you ask for a draft, the AI reads across all of it.
DocsThe shift
Before vs after
- Blank page two weeks before the NIH deadline
- Generic AI output that doesn't know your research
- Literature notes scattered across Notion, email, and PDFs
- 40% of your time on writing-adjacent tasks
- New grad students spend months discovering what your lab knows
- IRB and progress reports pushed until the last minute
- Specific Aims drafted in minutes, grounded in your publications
- AI that has read every paper in your library and your prior grants
- All literature, notes, and data in one River Space
- First drafts handled by River — you review, refine, and submit
- SOPs and protocols that onboard new members fast
- Administrative writing handled so you stay at the bench
How it works
From question to publication
Set up a research Space
Connect your Zotero library, upload prior grants, lab protocols, preliminary data, and past publications. River reads across all of it.
Write with citation-grounded AI
Ask for a literature review, a methods paragraph, a Significance section. River cites from your actual library — no hallucinated DOIs.
Iterate with co-authors and ship
Real-time editing with advisors, collaborators, and co-authors. Export to journal templates, arXiv-ready LaTeX, or NIH submission formats.
Templates
Popular templates for researchers
FAQ
Common questions
Stop spending 40% of your time writing about research
River handles the first draft of every grant, manuscript, and protocol. You review, refine, and submit. Start for free — no credit card required.