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River for Academic Labs

Plan grants, manage manuscripts, run literature reviews, and coordinate the lab's active projects. A workspace your trainees will actually use.

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Wu Lab · R01 Resubmission
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Specific Aims · R37 Resubmission
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Specific Aims · R37 Resubmission

Significance

Despite advances in checkpoint blockade, fewer than 25% of patients with advanced gastric cancer achieve durable response. The molecular basis for this resistance is unclear, and predictive biomarkers remain inadequate.

Aim 1

Identify single-cell transcriptional programs associated with response in a cohort of 84 patients treated at the consortium sites.

Aim 2

Validate the top 8 candidate programs in patient-derived organoids and a syngeneic mouse model with timed treatment cohorts.

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The status quo

What slows academic labs & principal investigators down today

  • Files scattered everywhereGrant drafts, manuscripts, and lit reviews are scattered across Dropbox, Drive, and email.
  • Version confusionSpecific Aims and figures go through 11 versions and you lose track of the latest.
  • Pipeline lives in your headThe manuscript pipeline lives in your head.
  • Same setup questions every yearTrainees ask the same setup questions every year because nothing is documented.
  • Two weeks lost to revisionsResponse-to-reviewers eats two weeks every revision cycle.

The work, organized

What academic labs & principal investigators use River for

R01 Grant Application

Specific Aims, Research Strategy, budget, and biosketches in one Space with deadline tracking.

Response to Reviewers

Address each reviewer comment systematically. River tracks what changed.

Manuscript Workspace

Introduction through Discussion, figures tracked, citations managed in one Space.

Literature Review Matrix

Synthesize your reference library into a structured thematic review.

IRB Protocol

IRB application sections, participant tracking, and renewal checklist.

Lab Grant Pipeline

Track every grant in progress, its deadline, and the lab's bandwidth.

Start here

R01 Grant Application

Start here. River gives you an R01 Space with Specific Aims, Research Strategy, biosketch tracker, budget justification, and a deadline timeline. Drop in your science and River drafts each section.

Included

  • Specific Aims doc
  • Research Strategy (Sig / Innov / Approach)
  • Introduction / Response to reviewers
  • Budget + justification sheet
  • Biosketch tracker
  • Grant pipeline dashboard

How River works

Everything lives inside a Space

A River Space holds all your documents, models, data, and context in one place. River AI reads across everything when you ask for a draft.

Docs
Sheets
Notes
Canvases
Decks
Tasks
Dashboards
Automations
Mail
AI chat
Files
River AI

The shift

Before vs after

Before
  • Grant drafts in 11 different versions
  • Pipeline tracked in your head
  • Trainee questions answered repeatedly
  • Response-to-reviewers is a two-week fire drill
After
  • One Space per grant with a single source of truth
  • Pipeline tracked with deadlines and bandwidth
  • Lab SOPs and protocols trainees can find
  • Reviewer responses drafted from the revision history

How it works

From a blank page to a working Space

1

Start with a template

Pick a template that matches the work. Pro forma, package, dashboard, or tracker.

2

Drop in your context

Add your project files, notes, client info, or a short description of what you are working on.

3

River organizes the inputs

The Space gets the right docs, sheets, checklists, and dashboards. River AI reads them automatically.

4

River drafts the artifacts

Memos, models, follow-ups, and reports come out of the Space, ready for your review.

5

Review, edit, and send

You stay in control. Export to PDF, push to your tools, or share a read-only link.

6

The Space stays live

Come back next cycle. Updated numbers, new docs, and River AI picks up where you left off.

Guides

Guides for academic labs & principal investigators

FAQ

Common questions

River gives you an R01 Space with Specific Aims, Research Strategy, biosketch tracker, budget justification, letters of support checklist, and a deadline timeline. Drop in your science, your collaborators, and prior aims. River drafts each section.

Start your first Lab Project Space

Pick a template and River builds the Space for you. Docs, sheets, checklists, and an AI assistant that already knows the work.